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Correspondence on 'Less is more for patients, practitioners, public and planet: a taxonomy for the harms of too much medicine

Gram et al ’s taxonomy of the harms of ‘too much medicine’ offers a valuable and timely framework for understanding how medical excess affects patients, practitioners, the public and the planet.1 ...
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Reconsidering the role of tramadol in chronic pain management

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be ...
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EBHC pyramid 5.0 for accessing preappraised evidence and guidance

Correspondence to: Dr Brian S Alper, DynaMed, EBSCO Health, 10 Estes Street, Ipswich, MA 01938, USA; balper{at}ebsco.com Practising evidence-based healthcare (EBHC) is integrating the best research ...
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How methodological pitfalls have created widespread misunderstanding about long COVID

The existing epidemiological research on long COVID has suffered from overly broad case definitions and a striking absence of control groups, which have led to distortion of risk. The unintended ...
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EBM Guidelines: Evidence-Based Medicine

This electronic resource aims to provide physicians with fast and easy access to practical guidelines linked to the best available research evidence. It covers a wide range of medical conditions and ...
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Estimates of the minimal important difference to evaluate the clinical significance of antidepressants in the acute treatment of moderate-to-severe depression

The efficacy of antidepressants in the acute treatment of moderate-to-severe depression remains a controversial issue. The minimal important difference (MID) is relevant to judge the clinical ...
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Diet–heart disease hypothesis is unaffected by results of analysis of recovered data from Minnesota Coronary Experiment

Correspondence to: Professor Murray Skeaff, Department of Human Nutrition, University of Otago, P.O. Box 56, Dunedin 9054, New Zealand; murray.skeaff{at}otago.ac.nz If you wish to reuse any or all of ...
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Superiority trials: raising the bar of null hypothesis statistical testing

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077 How can shared decision-making turn into paternalism – and how should we think about this ethically?

Introduction When a health professional overrides a patient’s preferences for the patient’s own good, we have a case of paternalism. Paternalism is commonly considered ethically problematic and ...
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Alcohol use and risk of dementia in diverse populations: evidence from cohort, case–control and Mendelian randomisation approaches

Objectives To investigate the relationship between alcohol consumption and dementia. Design Prospective cohort and case–control analyses combined with linear and non-linear Mendelian randomisation.
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Rapid reviews methods series: Guidance on literature search

This paper is part of a series of methodological guidance from the Cochrane Rapid Reviews Methods Group. Rapid reviews (RR) use modified systematic review methods to accelerate the review process ...
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Hidden risks of predictive models in healthcare

Joseph Alderman et al argue that predictive models in healthcare lack adequate oversight and regulation. They highlight the potential risks to patients and call for improved governance to ensure the ...