Recognized in the Biotechnology category of the 2025 Top Innovations contest, small Cas12l nucleases are versatile, ...

Is the key to understanding women’s higher rates of depression hidden in their DNA? A major international study by scientists ...

Researchers have created a detailed map of chemical modifications to DNA that occur in the human brain from the earliest ...

Most current approaches rely on adding nuclear localization signal (NLS) motifs to the ends of Cas9 to facilitate nuclear entry. However, this method is inefficient, and much of the Cas9 that is ...

Over the past two decades, synthetic biology has fueled advancements across a broad range of disciplines, including agriculture, bioremediation, biofuel production, and chemical manufacturing. Today, ...

The understanding of immune biology and the development of newer generations of immunotherapies have opened a new stage to ...

An international team led by a University of Pittsburgh School of Medicine scientist has created a first-of-its-kind resource ...

The microbiome-the trillions of bacteria, viruses, and fungi that live quietly in our body-plays a crucial role in shaping human health by providing a variety of micronutrients necessary for vital ...

Motor neuron diseases, such as amyotrophic lateral sclerosis (ALS) and hereditary spastic paraplegia (HSP), share physical ...

Liver cells are indispensable for research—for drug testing, to better understand diseases such as hepatitis, fatty liver, cirrhosis, or liver cancer and for development of future cell therapies.

Advances in cancer immunotherapy from immune checkpoint modulation to adoptive cell transfer of tumour-infiltrating ...

Traditional breeding and genetic modification methods have struggled to keep pace with the rapid evolution of plant viruses. CRISPR/Cas systems, originally derived from bacterial immune responses, ...