C&EN

N-Alkyl Sulfamates as a New Class of nsP2 Cysteine Protease Inhibitors with Broad-Spectrum Antialphaviral Activity

Structural Genomics Consortium, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States READDI AViDD Center, University of North ...
KMA Land

Trevor's Take: A statewide breakdown of the Class 8-Player playoff scenarios

(KMAland) -- It’s the final week of the regular season for Class 8-Player, A, 1A & 2A. Over the next few days, KMA Sports will break down the playoff scenarios from across the state. We begin with a ...
Frontiers

Physical activity and neuroplasticity in neurodegenerative disorders: a comprehensive review of exercise interventions, cognitive training, and AI applications

This review aimed to elucidate the mechanisms through which (i) physical activity (PA) enhances neuroplasticity and cognitive function in neurodegenerative disorders, and (ii) identify specific PA ...
Frontiers

Applying intervention mapping to develop a program for promoting short physical activity breaks during class time in upper secondary schools: the MOVE12 protocol study

Introduction: Physical inactivity is a global health challenge, exacerbated by increased screen time and sedentary behaviors. Enhancing physical activity levels at schools offers a promising approach ...
C&EN

Activity-Based Bioluminescent Logic-Gate Probe Reveals Crosstalk Between the Inflammatory Tumor Microenvironment and ALDH1A1 in Cancer Cells

Department of Chemistry, Beckman Institute for Advanced Science and Technology, and Cancer Center at Illinois, University of Illinois Urbana−Champaign, Urbana, Illinois 61801, United States ...