Understanding how cells turn genes on and off is one of biology's most enduring mysteries. Now, a new technology developed by ...
A company’s plan to edit the genomes of human embryos worries some researchers — but it might reflect the changing attitudes towards the controversial approach.
Amid unprecedented scientific progress in oncology, a growing body of evidence reveals a parallel and profound crisis in the ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. This longitudinal single-cell transcriptome ...
Most current approaches rely on adding nuclear localization signal (NLS) motifs to the ends of Cas9 to facilitate nuclear entry. However, this method is inefficient, and much of the Cas9 that is ...
In a world first, a bespoke gene-editing therapy benefitted one child. Now reseachers plan to launch a clinical trial of the ...
Credit: CHRISTOPH BURGSTEDT/SCIENCE PHOTO LIBRARY via Getty ... But if you want to use CRISPR for gene therapy, you must ...
Seven years after the first gene-edited babies were revealed, biotech startup Manhattan Genomics is reviving the idea of ...
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