Versatile gene-switch tool uses non-toxic molecule for safer research

Investigators at Weill Cornell Medicine have developed a versatile and non-toxic technology for controlling the activity of ...
EMBO Press

Early-stage lung adenocarcinoma affects DNA methylation and gene expression in adjacent tissues

Early-stage lung adenocarcinoma alters DNA methylation, mRNA transcription, and protein expression in adjacent tissues, exhibiting either steep changes at the tumor boundaries or shallow changes ...
Labroots

Oxygen Deprivation Alters Gene Expression, Raising Illness Risk

Oxygen is vital to the body. When levels of oxygen in the blood get too low, serious problems can arise. This can happen as... | Genetics And Genomics ...

Powerful tool can map gene regulation at single-nucleotide resolution

Understanding how cells turn genes on and off is one of biology's most enduring mysteries. Now, a new technology developed by ...
eLife

Glucose-stimulated KIF5B-driven microtubule sliding organizes microtubule networks in mouse pancreatic β cells

Sub-membrane microtubule array, known to prevent excessive glucose-stimulated insulin secretion, depends on kinesin-1 KIF5B, which moves microtubules to both generate and remodel this array, ...