The helicase unzips the double-stranded DNA for replication, making a forked structure. The primase generates short strands of RNA that bind to the single-stranded DNA to initiate DNA synthesis by the ...

32 P-label is introduced by incoming dGT 32 P molecule. The arrows indicate the sites of enzymatic hydrolysis. The bases of the template DNA strand are designated as clear boxes, and the bases in the ...

DNA, or deoxyribonucleic acid, is the hereditary material found in nearly all living organisms. It carries the genetic instructions for the development, functioning, growth, and reproduction of all ...

Life depends on double-stranded DNA unwinding and separating into single strands that can be copied for cell division. Scientists have determined at atomic resolution the structure of machinery that ...

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

A team has unlocked a decades old mystery about how a critical cellular process called DNA replication is regulated. A team of Florida State University researchers has unlocked a decades-old mystery ...

Long interspersed nuclear element-1 (LINE-1 or L1) is the only active, self-copying genetic element in the human ...