St. Jude researchers advance CASTs, enhancing precision and activity for next-generation genome-editing therapies.
Clonal hematopoiesis of indeterminate potential (CHIP) is a known risk factor for coronary artery disease, though its precise role in disease progression continues to emerge. This study leverages ...
Credit: CHRISTOPH BURGSTEDT/SCIENCE PHOTO LIBRARY via Getty ... But if you want to use CRISPR for gene therapy, you must ...
Cystic fibrosis (CF) therapeutics refer to treatments designed to manage and alleviate the symptoms of cystic fibrosis, a ...
Most current approaches rely on adding nuclear localization signal (NLS) motifs to the ends of Cas9 to facilitate nuclear entry. However, this method is inefficient, and much of the Cas9 that is ...
A lthough still in its early days, CRISPR has already been called the most powerful scientific tool of the century. Using ...
Seven years after the first gene-edited babies were revealed, biotech startup Manhattan Genomics is reviving the idea of ...
Arc Institute, Gladstone Institutes, and University of California, San Francisco, scientists have developed an epigenetic ...
Viruses are masters at taking over our cells: They disable our defenses and hijack the cellular machinery in order to multiply successfully. For example, the herpes simplex virus 1, which causes ...
A team of scientists has mapped the regions surrounding stem cells in planarians—small flatworms that are famous for being able to regrow whole bodies from small fragments—and discovered something ...
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