Most current approaches rely on adding nuclear localization signal (NLS) motifs to the ends of Cas9 to facilitate nuclear entry. However, this method is inefficient, and much of the Cas9 that is ...
Researchers have discovered a handful of new CRISPR-Cas systems that could add to the capabilities of the already transformational gene editing and DNA manipulation toolbox. Of the new recruits, one ...
CRISPR/Cas9 works by having CRISPR (pieces of DNA sequences) guide Cas9 (an enzyme that can cut and edit DNA) to edit, alter, or repair genes. Intellia has leveraged its expertise in CRISPR/Cas9 gene ...
Intellia Therapeutics has paused dosing in its Phase 3 MAGNITUDE trials after a patient experienced severe liver toxicity, as ...
A researcher at the University of Houston finds management of diabetic ketoacidosis may center around reducing ketone levels ...
A research team has successfully engineered a japonica rice variety using CRISPR/Cas9 to simultaneously optimize plant ...
A detailed look at the predicted structure of a new CRISPR-Cas tool that promises to expand the genomic editing and manipulating abilities of the original. Researchers at Duke University and North ...
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