Determining true HER2 status in breast cancers with polysomy using alternative chromosome 17 reference genes: Implications for trastuzumab therapy. Background: Systemic chemo- and chemoradiation ...

Different techniques can be used to identify novel methylated genes, such as methylation sensitive representational difference analysis (MS-RDA), CpG island microarray for methylation subtraction and ...

MSP: Methylation-specific PCR; MSRE: Methylation-sensitive restriction endonucleases; QMSP: Quantitative, methylation-specific PCR; X: Methylation associated with prognosis. Mohammad Obaidul Hoque, ...

The Genomics Core offers a variety of microarray analysis options for DNA and epigenetic studies. The Illumina BeadArray technology combined with the Illumina iScan Array Scanner allows for analysis ...

DNA and RNA methylation, initially thought to operate as distinct pathways, have been shown to interact closely, shifting our understanding of gene regulation. A team of researchers from the ...

Researchers at the University of Exeter have created a detailed temporal map of chemical changes to DNA through development and aging of the human brain, offering new insights into how conditions such ...

These days, you can order up a test to find out your biological age, an estimate of how quickly or slowly you're aging compared to your peers. It's based on an analysis of modifications in your DNA. I ...

MASPIN ("tumor suppressor shield"): MASPIN is a natural defense protein that blocks tumor invasion, regulates cell migration and angiogenesis, promotes apoptosis, and enhances treatment sensitivity.

In a recent study published in the journal Molecular Psychiatry, a team of researchers conducted a large-scale meta-analysis consisting of an epigenome-wide association study to understand whether ...

A life-altering experience “doesn’t just die with you,” one expert says. “It has a life of its own afterwards.” Scientists are gathering evidence that suggests emotional trauma can transcend ...